Valentino da Siena (died 1500) was a high ranking Borgia guard in Rome and Captain of one of the five Borgia towers that ruled over the Centro District.


In 1500, Ezio Auditore da Firenze, during his quest to liberate Rome from the Borgia rule, killed Valentino and burned down the tower in which he resided. Subsequently, the surrounding region was freed from Borgia oppression.

Two of Valentino's brothers, Pietro and Prospero, are also captains employed by the Borgia family. All three brothers flee when confronted by Ezio, and must be chased down.