It was constructed on the site of an ancient Christian basilica dedicated to John the Baptist between 706 and 715. The mosque was especially known for its three minarets, the Minaret of the Bride, the Minaret of Jesus and the Minaret of Quayt Bey.
- Each of the three minarets of the Umayyad Mosque serves as a view point. The highest view point in Damascus is located atop the Minaret of the Bride. However, in reality, the highest minaret of the Umayyad Mosque is the Minaret of Jesus, which, in-game, appears to be rather small in comparison.
- After the Ottomans conquered Damascus in 1516, Selim I attended the first Friday prayer in the Umayyad Mosque.
- During Damascus' Roman period, the ancient building served as a temple for Jupiter.
- In 1196, a mausoleum for Saladin was built next to the northwest corner of the mosque.