The Spanish conquest of the Inca Empire was one of the most important campaigns in the Spanish colonization of the Americas. After years of preliminary exploration and military skirmishes, 168 Spanish soldiers under Francisco Pizarro and their native allies captured the Sapa Inca Atahualpa in the Battle of Cajamarca. It was the first step in a long campaign that took decades of fighting but ended in Spanish victory in 1572 and colonization of the region as the Viceroyalty of Peru.
The Assassin Brotherhood tried to prevent a total collapse of the Empire by sending one of their own, Gonzalo Pardo, to discreetly influence the course of the conflict. The Assassin successfully infiltrated Pizarro's inner circle, becoming his favorite killer, but failed to prevent the death of Atahualpa in 1533. Three years later, with the help of a young woman named Quila, a disgraced Pardo redeemed himself by saving the life of Atahualpa's successor, Manco Inca Yupanqui during the Siege of Cuzco.