Rotterdam is the second-largest city in the Netherlands, located in the province of South Holland.
By 2012, the Assassins had a safehouse located in the city. On 19 December of that year, following William Miles' instructions, Harlan Cunningham left for the safehouse following the destruction of the Florence safehouse.[1]
In February 2014, Cunningham and his partner Arend Schut infiltrated an Abstergo Industries facility in Rotterdam and stole the Precursor box. After a firefight with Juhani Otso Berg's Sigma Team, Cunningham and Schut were forced to leave the artifact behind in order to escape.[2]