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Red-Handed was a virtual representation of one of Ezio Auditore da Firenze's genetic memories, relived by Desmond Miles in 2012 through the Animus.


Ezio Auditore came across a man who informed him that his wife was murdered by one of the Borgia's agents. Ezio then set off towards the antique baths where the killer was rumoured to be located.


Ezio came across a man who was filling up a grave with dirt.

  • Man: Please, don't call the guards. She would have wanted her burial here.
  • Ezio: Your wife?
  • Man: She was to be my wife...
  • Ezio: What happened?
  • Man: In the Colonna, she had a shop. The Borgia moved into the district and my wife refused to close. They found Monica with two thrown knives in her back.
  • Ezio: Do you know the killer?
  • Man: I heard of a woman who takes contracts for Cesare located near the antique baths.
  • Ezio: Leave before you are seen here.

Ezio travelled to the antique baths and located the killer and began to chase her.

  • Lia: Figlio di troia! Who sent you?
    Stop chasing me!
    Vattene via!

Ezio caught up to Lia and assassinated her.

  • Ezio: Requiescat in Pace (Rest in peace).


Ezio succeeded in killing one of the Borgia Templar agents.