In 48 BCE, while in the city's market with his sisters, Panchrates was kidnapped by men dispatched by Hetepi, a priest of Anubis and a member of the Order of the Ancients, losing one of his finger during the commotion. Panchrates was brought to the abandoned Temple of Hathor, where he was held captive in a cage. Hetepi used Panchrates' life to threaten his sisters into working for him. Due to the girls' duties with Apis bull's food, Hetepi had the priestesses poison sacred animal in the Temple of Ptah.
Eventually, thanks to the involvement of the Medjay, Aya and Bayek, Panchrates was freed by the latter. Panchrates was carried by Bayek back to his home located across the Temple of Ptah, where Aya and his sisters were waiting. Before reuniting with his sisters, Panchrates revealed the identity of the Lizard to Bayek, aiding him in his investigation.