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The panacea is a mythical substance which was named after the Greek goddess of universal remedy. It was thought to be have been capable of healing all diseases, along with possessing a connection to the process of creating the philosopher's stone.
- Although it was never explicitly mentioned that Bombastus and Giovanni Borgia managed to create one, panacea could be crafted in Project Legacy with the help of the philosopher's stone. As well as this, it was needed for a memory in the fourth chapter of the Rome set.