Madame John's Legacy is a house in New Orleans, built there after a fire destroyed much of the neighborhood.
- The house's name is derived from a short story by George Washington Cable, a writer that lived in New Orleans. The tale is about a placée called Madame John, who inherits the estate of a wealthy Frenchman, due to him never having married.
- In-game, Madame John's Legacy can be seen and visited as early as 1757, when Aveline is a child. In reality, the house wasn't built until 1788.
- A gentleman carrying a jeweled brooch could be found on one of the house's balconies.