- "Well, well. The Banker has a special evening planned. I will be delivering your payment. Give it here."
- ―Luigi to Egidio Troche, 1503.[src]
Luigi commanded a small group of soldiers responsible for gathering the debts of the Banker's clients, and for enforcing punishments should the payments not be made.
While Luigi took the money chest from Egidio and carried it into the Pantheon to count its contents, the Assassin Ezio Auditore da Firenze, who was intent on killing the Banker, infiltrated the landmark through the oculus on its roof.
As Luigi finished his count, he decided to give the order to have Egidio killed; however, Ezio assassinated Luigi from above before he could alert his men. Following this, Ezio stripped him of his guard uniform and wore it. The Assassin then impersonated Luigi, and entered the Pagan party at Trastevere.
- In Assassin's Creed: Brotherhood, Luigi appeared as a strong and high-ranking Borgia guard, but in the novelization, he was described as a withered man, and held a position that Egidio described as a "desk job".
- When Ezio equipped Luigi's outfit, he appeared to have the Borgia Captain Cape while Luigi does not have one.