Some time prior to 10 or 11 June 323 BC, Iltani had poisoned Alexander the Great, who died as a result on 10 or 11 June 323 BC.
By the time of the Renaissance, Iltani's sarcophagus had been moved to Santa Maria del Fiore in Florence. Fellow Assassin Ezio Auditore da Firenze explored her tomb and took the seal from her sarcophagus, which helped him to acquire the armor of Altaïr Ibn-La'Ahad.
- Iltani is the feminine form of a Babylonian word meaning "lucky" or "favored by the god(dess)".
- It is also the Babylonian name for the north wind.