Georges d'Amboise (1460 – 25 May 1510) was a French Roman Catholic Archbishop of Rouen during he reign of Louis XII of France. He simultaneously served as minister of state in which capacity he supported French influence in Italy.
A group of Italian Assassins interrogated Georges in Paris regarding the whereabouts of a missing Brotherhood member. Eventually, he gave them a list of names of ministers who were in league with the Borgia, whom the Assassins then killed.
In September 1503, Georges attended a Templar loyalist meeting in the Colosseum where he, along with other cardinals, informed Cesare Borgia that Giuliano della Rovere had been elected as Pope, rather than any pro-Borgia candidate. However, Cardinal d'Amboise was scared away from the meeting after the Italian Assassin Mentor, Ezio Auditore da Firenze, appeared to confront Cesare wielding an Apple of Eden.