Sometime around 1500, Friedrich planned to found an academic institution in the city of Wittenberg. Dedicated to religious reform, it would have teachings that openly questioned the actions of the House of Borgia. The Borgia attempted to prevent the opening of the university by sending Friedrich a large monetary bribe.
The Italian members of the Assassin Order became aware of this scheme and Mentor of the Italian Assassins Ezio Auditore da Firenze sent a team of Assassin apprentices from the Roman Assassins Guild to intercept the money, having them dress in bandit attire to prevent the Borgia from growing suspicious. After obtaining the illegal payment, they subsequently gave the money as an anonymous gift to Friedrich and his newly instituted academy.