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Saint Francis Borgia, S.J., 4th Duke of Gandía (1510 – 1572) was a Spanish Jesuit, Grandee of Spain and third Superior General of the Society of Jesus. He was the grandson of Juan Borgia and great-grandson of Rodrigo Borgia.

In 2012, Clay Kaczmarek included Francis Borgia in one of the Glyphs inside the Animus for Desmond Miles to find.

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