Cairo was founded by Jawhar al-Siqilli "The Sicilian", of the Fatimid dynasty, in the 10th century CE, but the land composing the present-day city was the site of national capitals whose remnants remain visible in parts of Old Cairo. Cairo is also associated with Ancient Egypt as it is close to the ancient cities of Memphis, Giza and Fustat which are near the Great Sphinx and the pyramids of Giza.
By the middle of the 13th century, both the Assassin Brotherhood and Knights Templar held presence in the city. In 1340, both the Assassins and Templars were looking for a Piece of Eden known as the Scepter of Aset. The Assassin Numa Al'Khamsin was heavily involved in the conflict in the city.
In late 2012, William Miles, the leader of the Assassins, traveled to Cairo to obtain a power source for the Grand Temple from the Egyptian Museum and arrived there on 9 December. Two days later, William was captured by the Templars' Sigma Team led by Juhani Otso Berg, and brought to Abstergo Industries' facility in Rome.