Used as a silent and deadly weapon, the blowpipe functioned in a similar way to poison darts. Edward obtained a blowpipe from Mary Read during a slave raid on the Assassin camp on Tulum, and made use of berserk and sleep darts.
Berserk darts would cause a target to attack anyone within close range, including guards, animals and Edward himself, for a short period of time. As soon as said period came to an end, the target would die. Sleep darts would cause targets to be knocked out for a short amount of time, allowing Edward to sneak past unnoticed. Both types of blowpipe darts could be used to cancel out the effects of the other.
Aveline's blowpipe contained lethal and berserk darts. The weapon first belonged to the Assassin François Mackandal, before it was passed down to Aveline by her Mentor, Agaté. While disguised in her lady persona, Aveline made use of a parasol gun, given to her by Gérald Blanc, which contained a mechanism similar to the blowpipe.
- Assassin's Creed III: Liberation
- The "Deadly Haystack" achievement could be earned by killing fifty enemies from a haystack using the blowpipe.
- The "Predator" achievement could be earned by killing an enemy with the blowpipe from a tree whilst using Eagle Vision.
- Assassin's Creed IV: Black Flag
- Civilians reacted to a berserk dart much the same way as regular guards, but, if Edward was detected by them, could not be engaged in a fight. Edward was only able to neutralize them by using a sleep dart or a firearm, though he could also wait until the dart's effect wore off.
- Berserk and sleep darts could be used to hunt wild animals, with sleep darts allowing for easier kills. Berserk darts were capable of killing animals (excluding monkeys) after the poison had run its cours, but it dd not make them anymore aggressive than they were normally.