Altaïr entered the Hospitalier Fortress, where he witnessed an escaped patient shouting about Garnier de Naplouse's cruel experiments to the gathered crowd. After the commotion was over, the Assassin entered Garnier's personal workspace within the fortress, and assassinated him.
Altaïr entered the Hospitalier fortress, when suddenly one of Garnier's patients came running through the halls, pursued by two guards.
- Patient: No, help! Help me! Help me! Please! You must help me!
Eventually they subdued him near the main entrance, as Garnier came out to investigate the commotion.
- Garnier: Enough, my child! I asked you to retrieve the patient, not to kill him! There, there. Everything will be alright.
- Patient: No!
- Garnier: Give me your hand.
- Patient: No, don't touch me! Not again!
- Garnier: Cast out this fear, else I cannot help you.
- Patient: Help me, like you helped the others?! You took their souls! I saw! I saw! But not mine! No! You'll not have mine!
Garnier then slapped the patient to silence him.
- Garnier: Take hold of yourself! Do you think this gives me pleasure? Do you think I want to hurt you? But you leave me no choice.
The patient was able to momentarily break free from one of the guards, and addressed the crowd around him.
- Patient: Every kind word, matched by the back of his hand! All lies and deception! He won't be content until all bow before him!
- Garnier: You should not have done that. Return him to his quarters! I'll be along once I've tended to the others.
- Patient: You can't keep me here! I'll escape again!
- Garnier: No. You won't. Break his legs, both of them.
Another guard came up to the patient and forcefully stepped on his knees, breaking both of his legs. The patient was then dragged back into the fortress.
- Garnier: I am so sorry, my child. Have you people nothing better to do?
As the crowd dispersed, Altaïr infiltrated Garnier's workspace and assassinated him once he had the chance.
- Altaïr: Let go your burden.
- Garnier: Ah, I'll rest now, yes. The endless dream calls to me. But before I close my eyes, I must know - what will become of my children?
- Altaïr: You mean the people made to suffer your cruel experiments!? They'll be free now to return to their homes!
- Garnier: Homes!? What homes!? The sewers? The brothels? The prisons that we dragged them from?
- Altaïr: You took these people against their will!
- Garnier: Yes, what little will there was for them to have. Are you really so naive? Do you appease a crying child, simply because he wails? "But I want to play with fire, father." What would you say? "As you wish"? Ah, but then you'd answer for his burns.
- Altaïr: These are not children, but men and women, full grown.
- Garnier: In body, perhaps, but not in mind; which is the very damage I sought to repair. I admit, without the Piece of Eden, which you stole from us, my progress was slowed. But there are herbs, mixtures and extracts. My guards are proof of this. They were madmen before I found and freed them from the prisons of their own minds. Ahh, and with my death, madmen they will be again.
- Altaïr: You truly believe you were helping them?
- Garnier: It's not what I believe, it's what I know.
Altaïr escaped the fortress and returned to the Bureau afterwards.
- Jabal: What news, Altaïr?
- Altaïr: Garnier is dead.
- Jabal: Then you should return to Masyaf with news of your victory.
- Altaïr: There is something else.
- Jabal: Speak it then! Or would you have me read your mind?
- Altaïr: What do you think he wanted from these people, that he would keep them and experiment on them as he did?
- Jabal: Yours is not to ask, but act, Altaïr! It doesn't matter what he did or why. Only that he's dead.
- Altaïr: But Garnier seemed to believe he was helping these people.
- Jabal: Is that what you saw?
- Altaïr: No. What I saw was not a place of healing, but of pain.
- Jabal: Then why are we having this conversation?
- Altaïr: I... I don't know. Forget I spoke of it.
- Jabal: I already have.
Altaïr then left the Bureau and returned to Masyaf's fortress, where he reported his progress to Al Mualim.
- Al Mualim: Have you news for me, Altaïr?
- Altaïr: Garnier de Naplouse is dead.
- Al Mualim: Excellent! We could not have hoped for a more agreeable outcome.
- Altaïr: And yet...
- Al Mualim: What is it?
- Altaïr: The doctor insisted his work was noble. And looking back, those who were supposedly his captives seemed grateful to the man. Not all of them, but enough to make me wonder. How did he manage to turn enemy into friend?
- Al Mualim: Leaders will always find ways to make others obey them. And that is what makes them leaders. When words fail they turn to coin. When that won't do, they resort to baser things - bribes, threats, and others types of trickery. There are plants, Altaïr, herbs from distant lands, that can cause a man to take leave of his senses. So great are the pleasures it brings, men may even become enslaved by it.
- Altaïr: You think these men were drugged, then? Poisoned?
- Al Mualim: Yes, if it truly was as you describe it.
- Altaïr: Herbs... This seems a strange method of control.
- Al Mualim: Our enemies have accused me of the same.
- Altaïr: The promise of paradise...
- Al Mualim: They think it is a garden, overflowing with women and pleasure. That I drug you as Garnier did his men and tempt you with its rewards.
- Altaïr: They do not know the truth of it.
- Al Mualim: Which is how it must be.
- Altaïr: But if they knew the truth of it, that all we seek is peace...
- Al Mualim: Then they would not fear us, and we would have no hold over them. Go, it is time you continued with your work. Another rank is restored to you, as is a piece of your equipment. We'll speak again when the next has fallen.
If Garnier was killed after Talal's death, different dialogue occurred.
- Al Mualim: Come in, Altaïr. You've done well. Three of the nine lay dead, and for this you have my thanks. But do not think to rest upon your laurels. Your work has just begun.
- Altaïr: I am yours to command, Master.
- Al Mualim: King Richard, emboldened by his victory at Acre, prepares to move south towards Jerusalem. Salāḥ ad-Dīn is surely aware of this. And so he gathers his men before the broken citadel of Arsuf.
- Altaïr: Would you have me kill them both then? End their war before it begins in earnest?
- Al Mualim: No. To do so would scatter their forces, and subject the realm to the bloodlust of ten thousand aimless warriors. It will be many days before they meet, and while they march, they do not fight. You must concern yourself with a more immediate threat - the men who pretend to govern in their absence.
- Altaïr: Give me names and I'll give you blood.
- Al Mualim: So I will. Abu'l Nuqoud, the wealthiest man in Damascus, Majd Addin, regent of Jerusalem, William of Montferrat, liege lord of Acre.
- Altaïr: What are their crimes?
- Al Mualim: Greed, arrogance, the slaughter of innocents. Walk amongst the people of their cities. You'll learn the secrets of their sins. Do not doubt that these men are obstacles to the peace we seek.
- Altaïr: Then they will die.
- Al Mualim: Another of your items is restored. Take it. See that it is put to good use. Return to me as each man falls, that we may better understand their intentions.
Al Mualim then dispatched three carrier pigeons, one for each city.
Altaïr assassinated Garnier de Naplouse, and returned to Masyaf to report his progress to Al Mualim.