The .38 Double Action is a classic, double-action revolver dating to the 19th century. Thanks to the double-action trigger, this model had an improved firing rate. In 1868, the Assassin twins Jacob and Evie Frye of the British Brotherhood received this weapon as a gift from Sergeant Frederick Abberline of the Metropolitan Police Service after they helped him arrest a considerable number of Blighters.
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- In real-life, the .38 Double Action in Assassin's Creed: Syndicate is called a Smith & Wesson Model 4.
- In Syndicate, the .38 Double Action is unlocked by reaching Loyalty Level 3 with Frederick Abberline.